<p>3-MA (60 µg) solutions were injected icv immediately before reperfusion. (A) The changes of LC3 after the treatment of 3-MA. 3-MA significantly decreased LC3-II levels at 24 h after I/R. Effect of 3-MA on infarct volumes (B) and neurological deficits (C). 3-MA significantly reduced the infarct volume, and ameliorate the neurological symptoms at 24 h after I/R. <sup>#</sup>p<0.05 versus I/R group.</p