Representative panels showing different expression intensity of MMP-9 in atrophic tubular nuclear compared to normal tubular cytoplasm nearby fibrotic renal parenchyma.

Abstract

<p>(A) no fibrosis with increased cytoplasm stain in normal tubules, (B) mild fibrosis with decreased cytoplasm stain in normal tubules and increased nuclear stain in atrophy tubules, (C) severe fibrosis with decreased cytoplasm stain in normal tubules, and (D) severe fibrosis with increased nuclear stain in atrophy tubules. (IHC stain, x 20).</p