<p>TGFβ1RI: TGFβ1 receptor I; TGFβ1RII: TGFβ1 receptor II.</p><p>TA: tubular adenoma; TVA: tubulovillous adenoma; I-IV AC: malignant stages of adenocarcinoma.</p><p>In brackets percentages of patients with alteration of the TGFβ1 receptor system. Minimal or low grade immunostaining was taken as an index of receptors’alteration.</p