JDP2 binds to the C-terminal part of the GR DBD.

Abstract

<p>A) A topological diagram of the GR500 fragment showing NTD (a.a. 1–420), AF1 (77–262), and DBD (421–481). B) Coomassie-stained SDS-PAGE gel showing the patterns of interactions between JDP2 or TBP_C and various fragments of the GR (indicated on the top). GST-pull down assay was performed to determine these <i>in vitro</i> interactions using purified recombinant protein in each case.</p