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Adhesion molecules expression analysis.

Abstract

<p>(A) Relative mRNA levels of VCAM-1, ICAM-1, e-selectin and p-selectin in aortic arches from p55<sup>+/+</sup>LDLR<sup>−/−</sup> (n = 10) and p55<sup>−/−</sup>LDLR<sup>−/−</sup> (n = 8) mice. Values are represented relative to expression in p55<sup>+/+</sup>LDLR<sup>−/−</sup> arches. (B) Immunohistochemical staining of VCAM-1 expression on sections from aortic valve areas indicating a less intense endothelial staining in p55<sup>−/−</sup>LDLR<sup>−/−</sup> mice. Original magnification×200. (C) Staining quantification. * p = 0.01 by Student's t-test. Error bars indicate SEM.</p

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