Prediction accuracies of NetNES, Wregex, NESsential, NESmapper, and consensus-based NES predictions using the ValidNES/SpNES test data.

Abstract

<p>Prediction accuracies were determined with the ValidNES dataset consisting of 185 proteins containing 205 LMB-sensitive NESs, as positive and negative data and the Sp-test negative dataset, containing 60 proteins from the Sp-protein dataset, as in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003841#pcbi-1003841-t001" target="_blank">Tables 1</a> and <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003841#pcbi-1003841-t002" target="_blank">2</a>.</p>a<p>Prediction with recommended PSSM configuration.</p>b<p>Prediction with relaxed PSSM configuration.</p>c<p>NESs with the probability values of ≥0.1 selected.</p>d<p>NESs with the probability values of ≥0.5 selected.</p>e<p>Percentage of proteins containing predicted NESs is indicated with parentheses.</p><p>Prediction accuracies of NetNES, Wregex, NESsential, NESmapper, and consensus-based NES predictions using the ValidNES/SpNES test data.</p