<p>Six studies described the need for rescue analgesics in thyroidectomy patients treated with dexamethasone versus placebo with or without concomitant anti-emetics (RR 0.65, 95% CI 0.50–0.83, <i>P</i> = 0.0008). There was no evidence of significant heterogeneity between RCTs (<i>P</i> = 0.25, <i>I</i><sup>2</sup> = 25%).</p