Additional file 2: Figure S2. of Autophagy capacity and sub-mitochondrial heterogeneity shape Bnip3-induced mitophagy regulation of apoptosis

Abstract

Flow diagram of time iteration loops for implementation of all update events in the multi-scale model. (Dark blue) Agent-based model updates (light blue) ODE updates for all mitochondria (dashed dark green) ODE update rules (dashed light green) mitochondrial state definitions (dashed gray) parameter values for model. (PDF 928 kb