Summary of spore-enriched protein mutant phenotypes.

Abstract

<p><i>C</i>. <i>neoformans</i> spores are produced through sexual development (above the gray bar). Sexual development occurs between haploid yeast of opposite mating types (<b>a</b> and α) and includes mate detection and cell fusion, dikaryotic filamentation, basidium formation and production of spores in chains. Spores can disperse and germinate into yeast (below the gray bar) to complete the life cycle. Gene names in red text are placed at the process in which deletion mutants show phenotypes. Six genes, <i>ISP3-7</i> and <i>SFH5</i>, did not result in detectable phenotypes in any assays.</p