Genome recovery from row sequence reads and <i>de novo</i> assembled contigs obtained from droplet MDA products of single and 10 <i>E</i>. <i>coli</i> cells.

Abstract

<p>(a) Comparison of genome recovery from raw sequence reads as a function of sequencing effort. Each plot shows the averaged percentage of genome recovery with SD from raw sequence reads for single (n = 3) and 10 (n = 3) <i>Escherichia coli</i> cells at >1× or >10× sequencing coverage. (b) Comparison of genome recovery from <i>de novo</i> assembled contigs as a function of sequencing effort. Each plot shows <i>de novo</i> assembly result in in-tube MDA and the droplet MDA.</p