Atg 5-siRNA had an enhancing effect on the production of mtROS similar to that of 3-MA. (A) Measurement of the mtROS production in THP-1 macrophage foam cells of different groups using flow cytometry. (B) Confirming the influence of Atg 5-siRNA on the expression of Atg 5 using Western blotting. Scambled siRNA is the negative control siRNA with the same nucleotide composition as Atg5 siRNA but which lacks significant sequence homology with the genome. (TIF 874 kb