Evoked local field potential recorded from lymph heart before and after addition of nifedipine and mibefradil dihydrochloride.

Abstract

A1) Representative trace of evoked local field potential (LFP) obtained from control and in the presence of nifedipine (20μM) (A2). A3) Bar charts show average peak to peak of evoked LFP amplitude calculated from control and after adding nifedipine (n = 10). The data for evoked LFP in the presence of nifedipine was normalised to data obtained from control. After adding nifedipine the average peak to peak of evoked LFP amplitude was significantly reduced (*** p<0.001) compared to the control. Error bars represent mean ± SEM (n = 10). B1) Representative trace of evoked local field potential (LFP) obtained from control and after adding mibefradil dihydrochloride (MD) (10μM) (B2). B3) Bar charts show average peak to peak of evoked LFP amplitude calculated from control and after adding MD (n = 13). The data for the evoked LFP in the presence of MD was normalised to data obtained from control. After adding MD the average peak of evoked LFP amplitude was significantly reduced (*** p<0.001) compared to the control. Error bars represent mean ± SEM (n = 13).</p