poster abstractThe Isoform of troponin I is uniquely produce in the adult human
myocardium and it overexpress at myocardial injury. Accordingly, Iso
troponin 1 level in plasma and other biological fluids can serve as diagnostic
and prognostic disease biomarkers. Our study focus on the design of a label
free ultrasensitive nanoplasmonic sensor by utilizing unique localized
surface Plasmon resonance (LSPR) property of highly sensitive gold
nanoprisms. Herein our study reveals that chemically synthesized
nanoprisms with 42 nm average edge lengths can be used in nanoplasmonic
sensor fabrication for the troponin detection. The limit of detection has been
found to be sub-picomolar concentrations in PBS buffer and we will explore
this sensing mechanism to detect Troponin I of myocardial infarction
patient’s samples