The present study is divided into two different parts. The first part will be devoted to detect risk factors for the non adherence to treatment in patients with isquemic cardiopathology. The aim of the second part of the study will be devoted to build and describe the landmark methodology which enables to estimate, in an unbiased way, the survival functions when covariate membership is not defined at baseline but during the follow-up. This methodology will be also applied to an available data set
