目的：1．观察坐骨神经慢性损伤大鼠机械痛阈及热痛阈的变化，测定坐骨神经慢性压迫性损伤(Chronicconstrictioninjury,CCI)大鼠脊髓N-甲基D-天冬氨酸受体2B亚基(N-methyl-D-asparticacidreceptor2B,NR2B)、核因子-κB(nuclearfactor-kappaB,NF-κB)和诱导型一氧化氮合酶(Induciblenitricoxidesynthase,iNOS)的表达，探讨神经病理性疼痛的发病机制。 2．观察恩再适对CCI大鼠痛觉过敏及脊髓NR2B、NF-κB和iNOS表达的影响。 方法：1．56只180-220g雄性SD大鼠随...AIM: 1.To observe expression of NR2B, NF-κB and iNOS in the spinal cord in rat model of chronic constriction injury (CCI) of the sciatic nerve. 2.To observe the effects of analgecine on hyperalgesia and expression of NR2B, NF-κB and iNOS in the spinal cord in rat model of the chronic constriction injury of the sciatic nerve. MERHODS: 1.Fifty-six adult male Sprague-Dawley rats weighing 180-220 g...学位：医学硕士院系专业：医学院_外科学学号：2452011115340
