目的探讨变应性鼻炎与鼻中隔偏曲的关系,为伴有鼻中隔偏曲的变应性鼻炎手术治疗提供依据。方法选取72例伴有鼻中隔偏曲的变应性鼻炎的患者,随机分成A、b二组,A组行鼻中隔黏膜下矫正术加常规药物治疗、b组采用常规药物治疗。选取36例不伴有鼻中隔偏曲的变应性鼻炎患者为C组,行鼻中隔黏膜下剥离术加常规药物治疗。随访12个月,观察疗效,进行相关性分析。结果治疗后1周A、b、C三组的总有效率均为100%,1个月时三组的总有效率分别为A组:100%、b组:18.8%、C组:100%,各组之间疗效差异有统计学意义,A、C组疗效明显高于b组,6个月时三组的总有效率分别为A组:95%、b组:全部复发、C组88.9%,A、C组疗效差异无统计学意义,12个月时A、C组的总有效率分别为A组:90%、C组:69.4%,二组疗效差异有统计学意义,A组高于C组。结论予伴有鼻中隔偏曲的变应性鼻炎患者行鼻中隔黏膜下矫正术治疗,有较好疗效。变应性鼻炎发病与鼻中隔偏曲有关,对伴有鼻中隔偏曲的变应性鼻炎患者可行鼻中隔黏膜下矫正术治疗。Objective To study the relationship between allergic rhinitis and deviation of nassal septurm and to provide reference for the surgical treatment of perennial allergic rhinitis with septal deviation.Methods 72 cases of perennial allergic rhinitis with septal deviation were randomly assigned to two groups: group A and group B.Group A received nasal septal reconstruction with routine therapy.Group B were treated with routine therapy.A total of 36 cases allergic rhinitis without septal deviation were Group C, and they also received nasal septal reconstruction with routine therapy.During the follow-up of 12 months, we observed the effects and did the relavent analysis.Results After 1 week follow-up, the overall effective rate of the three groups were all 100%.After 1 month follow-up, the overall effective rate of group A,B and C was in turn 100%, 18.8%,100%,There was significant difference among groups.The efficacy of group A and C was higher than that of group B.After 6 months follow-up, the overall effective rate of group A and C was in turn 95%, 88.9%.Group B: all recrudescent.No significant difference was found between group A and C .After 12 months follow-up, the overall effective rate of group A and C was in turn 90%, 69.4%.There was significant difference between group A and C.The efficacy of group A was higher than that of group B .Conclusion There is a relation between allergic rhinitis and deviation of nassal septurm.Application of nasal septal reconstruction proved useful for the treatment of the perennial allergic rhinitis patients with septal deviation
