Development of poly (3-hydroxybutyrate) (P(3HB))/bioactive glass composite system for biomedical applications

Abstract

P(3HB) was produced from a novel gram-positive micro-organism (Bacillus cereus SPV) using biotechnology routes based on a 14 L fermentation strategy. 45S5 Bioglass (BG) particles of micrometer (2 wt%) caused MG-63 osteoblast cell death, whereas in low concentrations MWCNTs increased the cell proliferation. Overall, the novel composites developed in this project represent a very attractive group of materials for bone tissue engineering applications.EThOS - Electronic Theses Online ServiceGBUnited Kingdo