Investigation of the electronic and magnetic hyperfine properties of the copper(II) and zinc(II) complexes.

Abstract

The treatment of cancer diseases are a dangerous world wide\ud problem that requires the usage of extreme techniques such as surgery and\ud the use of metallodrugs (pharmaceutical metal complexes). The most famous\ud antitumor metal complex is the cisplatin but it has several collateral effects\ud that cause injuries in the patients. This opens opportunity to research and\ud develop alternatives that could increase the efficiency or reduce the body\ud damage. However, metal complexes are a difficult class of compound to deal\ud with, often requiring theoretical methods to guide the characterization of the\ud molecules. We investigate the electronic and magnetic hyperfine properties\ud of the copper(ll) and zinc(ll) complexes of 2(3H)- Furanone,dihydro-3-\ud (hydroxyphenylmethyl)-4-[(1-methyl-1 H-imidazol-4-yl)methyi]-,[3S[\ud 3a(R*),4b]] (Epiisopiloturine) metal complex, an alkaloid that show activity\ud against cancer and schistosomiasis