Probijajuća bol (PB) kod karcinoma definira se kao tranzitorna egzacerbacija boli kod bolesnika sa stabilnom i kontroliranom osnovnom boli. PB i osnovna bol odvojene su komponente karcinomske boli i zahtijevaju odvojen terapijski pristup. Liječenje PB-a uključuje interdisciplinarni i multimodalni pristup. Uobičajeno liječenje PB-a provodi se dodatnim dozama opioida, poznatim kao spasonosna medikacija.Breakthrough cancer pain is defined as transient pain exacerbation in patients with stable and controlled basal pain. Persistent and breakthrough pain are distinct components of cancer pain and require separate management. The management of breakthrough cancer pain should involve an interdisciplinary and multimodal approach. A specific assessment and precise pain characterization are essential to plan the most appropriate treatments. The usual approach to managing breakthrough pain is with supplemental doses of opioids, also known as rescue medication