Quantitative estimation of antibodies in the immunoglobulin classes of the mouse. I. Effect of adjuvants on the antibody response to human serum albumin and keyhole limpet haemocyanin
Antibody activity against HSA and KLH was present in all five immunoglobulin classes of BALB/c mice. Bordetella pertussis vaccine was more effective in stimulating antibody production against HSA than against KLH and IgG(1) and IgG(2b) antibody were affected more than the antibody present in the other immunoglobulin classes. The results are discussed in relation to the differing thymic dependence of these two antigens
