Roder, Karim

Schweizer, Michael

Wolf, Siegmund S.

Electrophoretic mobility shift assay (EMSA) and in vitro transcription/translation show that NF-Y binds to the inverted CCAAT-element in the promoter of the rodent spot14 gene. The NF-Y-binding sequence has been shown to be responsible for basal activity in H4IIE. Given the similar role found for the inverted CCAAT-element in the promoter of the FAS gene, NF-Y may have an important function in the control of lipogenesis.</p

Dependence of rat spot14 promoter activity on NF-Y binding to the inverted CCAAT-element at - 100

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