Susceptibility Breakpoint for Enrofloxacin against Swine Salmonella spp

Abstract

ABSTRACT Susceptibility breakpoints are crucial for prudent use of antimicrobials. This study has developed the first susceptibility breakpoint (MIC ≤ 0.25 μg/ml) for enrofloxacin against swine Salmonella spp. based on wild-type cutoff (CO WT ) and pharmacokinetic-pharmacodynamic (PK-PD) cutoff (CO PD ) values, consequently providing a criterion for susceptibility testing and clinical usage of enrofloxacin. </jats:p