Marker Analysis with APRIORI-based Algorithms

Abstract

Abstract. In genetic studies, complex diseases are often analyzed searching for marker patterns that play a significant role in the susceptibility to the disease. In this paper we consider a dataset regarding periodontitis, that includes the analysis of nine genetic markers for 148 individuals. We analyze these data by using two APRIORI-based algorithms: APRIORI-SD and APRIORI with filtering. The discovered rules (especially those found by APRIORI with filtering) confirmed the results published on periodontitis.