The study was funded by grants from the Research Council Norway (ID:302191), the University of Edinburgh's Data Driven Innovation Initiative (Scottish Funding Council Beacon ‘Building Back Better’ Call), and the Biotechnology and Biological Sciences Research Council, including the institutional strategic programme grants BBS/E/D/10002071, BBS/E/RL/230001C, BBS/E/D/20002174, BBS/E/RL/230002B, and the responsive mode grants BB/W005859/1 and BB/W008564/1. NH is supported by a Wellcome Trust Senior Research Fellowship in Clinical Science (ref. 219542/Z/19/Z). UG is supported by the Research Council of Norway (ID:274635).Peer reviewe