Linezolid- and Vancomycin-resistant Enterococcus faecium in Solid Organ Transplant Recipients: Infection Control and Antimicrobial Stewardship Using Whole Genome Sequencing
A vancomycin-resistant enterococci outbreak occurred in a large organ transplant center and remained undetected due to limitations of conventional testing methods. Whole genome sequencing revealed a subpopulation of organisms harboring the G2576C mutation affecting 23S ribosomal RNA and conferring resistance to linezolid
