Ryanodine receptor 1 (RyR1) localization


Cross-sections of the gastrocnemius (a-h) and soleus (i-p) muscles were stained with anti-RyR1 antibody. Asterisks indicate normal immunoreactivity (IR) in the cytoplasm and subsarcolemma of RyR1 (a-d, i-p). Arrows indicate muscle fiber with ectopic RyR1 IR (e-h). Scale bar = 50 μm. GAS, gastrocnemius muscle; SOL, soleus muscle; 3M, 3-month-old mice; 24M, 24-month-old mice.</p

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