Multiple sclerosis (MS) is an immune system demyelinating and neurodegenerative disease of the central nervous system, and the main source of non-traumatic neurological disability in young adults. Successful management requires a complex way to deal with control acute attacks, manage progressive declining, and remediate bothersome or handicapping side effects related with this disease. Striking advances in treatment of all types of MS, and particularly for relapsing disease, have well changed the long-term outlook for some patients. There likewise has been a calculated change in figuring out the immune pathology of MS, away from a simply T-cell interceded model to acknowledgment that B cells play a vital part in pathogenesis. The rise of higher-efficacy drugs requiring less frequent administration have made these favoured choices with regards to tolerability and adherence. Numerous specialists currently suggest utilization of these as first-line treatment for some patients with early disease, before long-lasting handicap is evident