Greenslade, L

Morgan, MY

Vadera, S

UCL Discovery

BSG 2016 - Abstract SubmissionLiverBSG16-ABS-1453HEALTH-RELATED QUALITY OF LIFE, PSYCHOLOGICAL WELL-BEING AND SOCIOECONOMIC IMPACT INPATIENTS WITH CIRRHOSIS AND THEIR CAREGIVERSS. Vadera* 1, L. Greenslade2, M. Y. Morgan11UCL Institute for Liver & Digestive Health, Division of Medicine, Royal Free Campus,University College London,Hampstead, 2The Sheila Sherlock Liver Centre, Royal Free Hospital, Royal Free London NHS Foundation Trust, London,United KingdomDoes this abstract contain original data?: YesWill this abstract be published/presented prior to June 2016?: NoThis abstract is: None of the aboveDoes your Endoscopy abstract include a video?: NoPatient’s consent: NoPreferred presentation type: Oral or PosterIntroduction: The psychological, social and economic consequences of a diagnosis of cirrhosis, for both patients andtheir families/friends, are not routinely assessed in the UK. The aim of this study was to assess Health-related Quality ofLife (HRQoL), psychological well-being and socioeconomic burden in a random sample of patients with cirrhosis and theircaregivers. Methods: The patient population comprised 51 patients with cirrhosis (38 men: 13 women; mean age 55 [21-87] yr) withno evidence of fluid retention utilizing hospital inpatient/outpatient facilities and 15 patients (nine men: six women; meanage 60 [36-82] yr) attending the day-ward for large volume paracentesis (LVP). HRQoL was assessed using the genericEQ-5D questionnaire. The frequency of anxiety and depression was assessed using the Beck Anxiety (BAI) andDepression (BDI) inventories. The impact on employment and disease–related costs were assessed using an adaptedfinancial questionnaire (1). Caregivers’ burden was assessed in 20 relatives/friends using the Perceived CaregiversBurden Scale and the Zarit Burden Interview. All patients/caregivers were interviewed to obtain additional information onpsychosocial and general well-being. A control population of 52 individuals (28 men: 24 women; mean age 49 [26-68] yr)was also included.Results: HRQoL was significantly impacted in both the general patients with cirrhosis and in those undergoing LVP,compared to controls (EQ-5D: 0.51±0.32 and 0.52±0.18 vs. 0.92±0.11; p<0.001). The frequency of anxiety anddepression was also significantly increased in the general patients with cirrhosis (BAI 18.9±15.9: BDI 17.6±12.7;p<0.001) and those undergoing LVP (BAI 17.1±11.0: BDI 15.6±7.4; p<0.001), compared with controls (BAI 4.3±4.7: BDI4.5±4.5; p<0.001). Two-thirds of the general patients with cirrhosis and 100% of those undergoing LVP wereunemployed; 50% considered their diagnosis had impacted on their employment status. The majority of patients werefinancially impacted, with direct out-of-pocket expenses, e.g. for hospital transport costs, of £350-£1500 since diagnosis.Approximately 15% of caregivers reported moderate anxiety while 5% reported moderate depression. The majority ofcaregivers were assessed as having a moderate degree of burden.Conclusion: Patients with cirrhosis have poor HRQoL and are often depressed and anxious; in addition they frequentlyhave undisclosed socioeconomic difficulties. Caregivers are also detrimentally affected. Attention needs to be paid to theholistic needs of patients and careers, particularly in relation to their psychosocial and financial well-being. References: 1. Bajaj JS et al. Am J Gastroenterol 2011;106:1646-53.Disclosure of Interest: None Declared

Health-Related Quality of Life, Psychological Well-Being and Socioeconomic Impact in Patients With Cirrhosis and Their Caregivers

http://discovery.ucl.ac.uk/1544407/1/Morgan_BSG%20HRQoL%202016.pdf

Health-Related Quality of Life, Psychological Well-Being and Socioeconomic Impact in Patients With Cirrhosis and Their Caregivers

Abstract

Similar works

Full text

Available Versions

UCL Discovery