The Gene Ontology (GO) is a comprehensive resource
of computable knowledge regarding the functions
of genes and gene products. As such, it is extensively
used by the biomedical research community
for the analysis of -omics and related data. Our
continued focus is on improving the quality and utility
of the GO resources, and we welcome and encourage
input from researchers in all areas of biology. In
this update, we summarize the current contents of
the GO knowledgebase, and present several new features
and improvements that have been made to the
ontology, the annotations and the tools. Among the
highlights are 1) developments that facilitate access
to, and application of, the GO knowledgebase, and
2) extensions to the resource as well as increasing
support for descriptions of causal models of biological
systems and network biology. To learn more, visit
http://geneontology.org/
