The chemical industry is responsible for about 5% of global CO2 emissions and is key to achieving net-zero targets. Decarbonizing this industry, nevertheless, faces particular challenges given the widespread use of carbon-rich raw materials, the need for high-temperature heat, and the complex global value chains. Multiple technology routes are now available for producing chemicals with net-zero CO2 emissions based on biomass, recycling, and carbon capture, utilization, and storage. However, the extent to which these routes are viable with respect to local availability of energy and natural resources remains unclear. In this review, we compare net-zero routes by quantifying their energy, land, and water requirements and the corresponding induced resource scarcity at the country level and further discuss the technical and environmental viability of a net-zero chemical industry. We find that a net-zero chemical industry will require location-specific integrated solutions that combine net-zero routes with circular approaches and demand-side measures and might result in a reshaping of the global chemicals trade
