Microansamycins J and K from <i>Micromonospora</i> sp. HK160111mas13OE

Abstract

Microansamycins were novel pentaketide ansamycins isolated from Micromonospora sp. HK160111mas13OE with AHBA-C2-C2-C3-C3 skeleton and diverse post-PKS modifications. In this paper, two new congeners, namely microansamycins J (1) and K (2), were identified based on their NMR, HRESIMS data and compared with those of microansamycins F and E. Neither showed antibacterial activity against Staphy­lococcus aureus ATCC25923 and Escherichia coli at 40 µg/mL.</p