e recently designed new class of interactive meta-holographic display with a combination of polarization multiplexing metasurface and stimuli-responsiveness of liquid crystals (LCs). By leveraging our recent works, here we propose the holographic chemical sensor that autonomously senses a target chemical and reports it via direct holographic alarm. Additionally, by doping a chemical selector into LCs, we demonstrate our system to be able to not only precisely control selectivity but also sensitivity toward programmed chemical.1