Free-thyroxine index in mania and depression

Abstract

Although free-thyroxine index is commonly used as a reliable method of thyroid function investigation,1,2 only Rybakowski and Sowinski3 have used this method for the assessment of thyroid function in mania. In depression, determination of free-thyroxine index by four research groups3,6 revealed contradictory results. For these reasons, it was thought that further research in this area would be justified. © 1978