Purpose To compare the utility of fluorescein angiography (FA) and
optical coherence tomography (OCT) as diagnostic adjuncts in evaluating
symptomatic patients with choroidal neovascularisation (CNV) due to
multifocal choroiditis (MFC).
Methods Patients with CNV due to MFC were retrospectively evaluated in a
consecutive fashion. Fundus photography, FA, OCT and biomicroscopy were
used to establish the diagnosis. Primary outcome measures included CNV
classification (type 1 or occult and type 2 or classic) location and the
associated FA and OCT findings.
Results Twenty eyes from 17 patients were included in the study. In 19
eyes (95%) the FA revealed CNV type 2; in one eye (5%) the type of CNV
was indeterminate due to a subretinal haemorrhage that covered the
lesion. Thirteen eyes had OCT imaging and all revealed hyper-reflectance
beneath the neurosensory retina. However, only 53.8% revealed
subretinal fluid (SRF) or intraretinal cystic abnormalities.
Conclusions The CNV in MFC is virtually always type 2, or so-called
classic CNV, with vessels beneath the neurosensory retina. Except when
blocked by subretinal blood, the neovascularisation is clearly
demonstrated by FA. In contrast, only 53.8% of these eyes showed clear
evidence of actively proliferating neovascularisation on OCT. Therefore,
eyes suspected of having CNV in MFC should be evaluated with FA