Blondeel, Phillip

Braems, Geert

Cocquyt, Veronique

De Maeseneer, Daan

Denys, Hannelore

Depypere, Herman

STRIJBOS, MICHIEL

Van Belle, Simon

Van den Broecke, Rudy

English

Ghent University Academic Bibliography

MULTICENTER CROSS-SECTIONAL STUDY COMPARING QUALITY OF LIFE, BODY IMAGE AFTER BREAST CANCER SURGERY D.J. De Maeseneer MD 1, M. Strijbos MD 1, P. Blondeel MD PhD 2, R. Van den Broecke MD PhD 3, H. Depypere MD PhD 3,  G. Braems MD PhD 3, H. Denys MD PhD 1, V. Cocquyt 1   1  Department of Medical Oncology, University Hospital Ghent, Belgium   2 Department of Plastic Surgery, Ghent University, Belgium 3 Department of Gynecology, University Hospital Ghent, Belgium Goals •  Early breast cancer patients •  8 breast cancer clinics •  EORTC QLQ-30, BR-23, Body Image Scale •  Univariate and regression analysis In our study, mastectomy with reconstruction patients showed the best global health status scores outperforming both BCS and mastectomy without reconstruction patients. Differences were not large and not statistically significant in univariate analysis. We confirmed the impact of type of breast cancer surgery on body image. Using validated questionnaires and excluding patients with a short interval after surgery, we found that body image in the BCS group was significantly better compared to the two mastectomy groups. There is a small benefit of reconstruction after mastectomy, which was not significant. In early breast cancer, pre-operative multidisciplinary counselling seems necessary, explaining possible implications of each surgical treatment choice. Selected patient characteristics are listed in table 1: Results Methods Conclusion ©  2013 University Hospital Ghent Significant differences between treatment groups are highlighted in red.  Current guidelines propose both breast conserving surgery (BCS) and mastectomy with or without reconstruction in early breast cancer patients. Although a more conservative surgical approach aims to improve post-operative quality of life (QoL), multiple studies have failed to show a clear benefit. This study uses an extensive database of a post-operative QoL survey in Flanders to discover small but significant differences in quality of life and body image between BCS, mastectomy and mastectomy followed by reconstruction. We analyzed data from 655 breast cancer patients. Patients characteristics were significantly different between treatment groups (table 1). Global health status showed an advantage of mastectomy with reconstruction patients, but this was not significant (P=0.066). Body image was significantly better in BCS patients compared to both mastectomy groups, which showed no significantly different scores (table 2). Multivariate analysis (not shown) did show a clear beneficial effect of BCS on global health scores compared to the mastectomy without reconstruction group (P=0.002), but not in comparison with the mastectomy with reconstruction group. Body image scores stayed in favour of BCS in multivariate analysis.  Quality of life scores. Median of the QoL scores with interquartile range between brackets. Global health status and significantly differing calculated scores are shown in table 2:  Higher QoL scores mean a better outcome, with exception of the Body image score (BIS) where lower scores mean a better body image. Higher symptom scores mean a higher degree of symptoms. 

Multicenter cross-sectional study comparing quality of life, body image after breast cancer surgery

https://biblio.ugent.be/publication/4085477/file/4224607.pdf

Multicenter cross-sectional study comparing quality of life, body image after breast cancer surgery

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Ghent University Academic Bibliography