Maspin is a tumour suppressor that inhibits breast cancer tumour metastasis in vivo

A Hossain; A Neri; AP Gilmore; B Welm; CH Streuli; CL Wilson; D Hanahan; DG Hall; EI Deryugina; EW Thompson; FE Domann; FS Kittrell; G Bergers; G Ellison; HY Shi; J Oh; JE Fata; JM Prince; JS Reis-Filho; KB Reddy; M Johnsen; M Lelekakis; M Zhang; MD Sternlicht; MD Sternlicht; MS Murthy; N Maass; N Maass; OE Blacque; R Yasumatsu; RE Seftor; RH Xing; RS Talhouk; S Machtens; S Meiners; S Pullan; S Sheng; S Sheng; SA Rabbani; SR Lakhani; T Gudjonsson; TH Vu; WG Cance; WG Stetler-Stevenson; Z Werb; Z Zou; Z Zou

Maspin is a tumour suppressor that inhibits breast cancer tumour metastasis in vivo

Authors: A Hossain
A Neri
AP Gilmore
B Welm
CH Streuli
CL Wilson
D Hanahan
DG Hall
EI Deryugina
EW Thompson
FE Domann
FS Kittrell
G Bergers
G Ellison
HY Shi
J Oh
JE Fata
JM Prince
JS Reis-Filho
KB Reddy
M Johnsen
M Lelekakis
M Zhang
MD Sternlicht
MD Sternlicht
MS Murthy
N Maass
N Maass
OE Blacque
R Yasumatsu
RE Seftor
RH Xing
RS Talhouk
S Machtens
S Meiners
S Pullan
S Sheng
S Sheng
SA Rabbani
SR Lakhani
T Gudjonsson
TH Vu
WG Cance
WG Stetler-Stevenson
Z Werb
Z Zou
Z Zou
Publication date: 1 January 2002
Publisher: BioMed Central
Doi

Abstract

Maspin is a member of the serpin family of serine proteases and functions as a tumour suppressor. A study using a new syngeneic mouse model for breast cancer suggests that maspin can inhibit metastasis in vivo

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