Herein,
we synthesized and characterized a binuclear copper(I)
complex supported by the indolyl-based ligand. Employing this complex
as catalyst, we have developed a three-component intermolecular trifluoromethylazolation
of alkenes to deliver various trifluoromethylated azole derivatives.
The method features exclusive chemo- and regioselectivity, a broad
scope of alkenes and oxazoles, thiazoles, and good tolerance of functional
groups under mild conditions. Preliminary mechanistic studies support
a radical process for the transformation