Abstract: Learning challenges seem to persist in different ways in rural based universities. These challenges have led to increase in drop-out rates, as well as several menaces in the African society. Hence, this study explored the learning challenges among undergraduate students in rural universities in Africa. Review of related literatures revealed that undergraduates in the African rural universities experience common learning challenges which include: cognitive learning challenge, poor academic foundation, academic malpractice amongst academic staff and students, as well as lecturer-students’ relationship. These are caused by lack of facilit ies, students’ family socio-economic background, amongst others. The study therefore recommends that the necessary facilities and structures needed to facilitate teaching and learning practices should be provided. More lecturers should be recruited. Cordial student- lecturer relationships should be encouraged and promoted. In addition, policies that will ensure safety on campus, adoption and use of the most suitable language of instruction amongst others should be established. The study suggests the need for additional focus on the quality added to university education in developing African nations