This article will provide the practising obstetrician with a general guide to the structure and interpretation of the histopathology report, with a focus on placental and perinatal autopsy reports. The relevance and readability of a histopathology report is heavily dependent on the quality of clinical information provided by the referring clinician. Walkthroughs of example placental and autopsy reports are provided, along with examples of pathologies and their possible significance to the underlying diagnosis