The aim of this study was to estimate the costs of treatment of
children who present with the signs and symptoms of invasive bacterial
diseases in Khanh Hoa province, Viet Nam. The study was an
incidence-based cost-of-illness analysis from the health system
perspective. The hospital costs included labour, ma-terials and capital
costs, both direct and indirect. Costs were determined for 980
children, with an average age of 12. 67 months (standard
deviation\ub1 11. 38), who were enrolled in a prospective
surveillance at the Khanh Hoa General Hospital during 2005- 2006. Of
them, 57% were male. By disease-category, 80% were suspected of having
pneumonia, 8% meningitis, 3% very severe disease consistent with
pneumococcal sep-sis, and 9% other diseases. Treatment costs for
suspected pneumonia, meningitis, very severe disease, and other
diseases were US31,US 57, US73,andUS 24 respectively. Costs
ranged from US24toUS 164 across different case-categories. Both
type of disease and age of patient had statistically significant
effects on treatment costs. The results showed that treatment costs for
bacterial diseases in children were consid-erable and might differ by
as much as seven times among invasive pneumococcal diseases. Changes in
costs were sensitive to both age of patient and case-category. These
cost-of-illness data will be an important component in the overall
evidence base to guide the development of vaccine policy in Viet Nam