The antibiotic sensitivity pattern and plasmid profile of Escherichia
coli , Vibrio and Salmonella species isolated from well and river
water sources in Oproama Community were investigated. Antibiotic
sensitivity profiles of the bacteria (Escherichia coli, Vibrio sp. and
Salmonella sp.) isolated from the water showed high sensitivity to
oflaxicin, nalidixic acid and nitrofurantoin and high resistance to
amoxicillin, augumentin, cotrimazole and tetracycline. Multi antibiotic
resistant index (MARI) as high as 0.375 (Escherichia coli: E9; Vibrio
spp.: V3, V4, V10; Salmonella spp.: S1, S9), 0.5 (Vibrio spp.: V2;
Salmonella spp.: S2, S4) and 0.75 (Salmonella spp.: S7) were recorded
after curing the plasmids with sodium deodecyl sulphate (SDS). The
plasmid profiles revealed that 60% of the isolates harboured detectable
plasmids with sizes up to 23.130 kb