The paper shows the preliminary results of a numerical analysis aimed at investigating the response – in terms of onset and development of damage – of a masonry building with shallow foundations undergoing slow-moving landslide-induced displacements. The analysis is performed by applying the Equivalent Frame method to a representative damaged masonry building located in the historic centre of Lungro town (Calabria region, southern Italy) interacting with a slow-moving landslide in complex-structured and weathered soils. A three-dimensional settlement pattern is imposed at the foundation level by way of a displacement-controlled analysis that makes use of both vertical and horizontal displacement information gathered from conventional (ground-based) and innovative (remote-sensing) monitoring techniques. The obtained outcomes, owing to the good matching of the modeled building response with damage data collected by multi-temporal in-situ surveys, can help in defining representative building-landslide models to be used for predicting and preventing the damage in slow-moving landslide-affected urban areas