D'haeseleer, Evelien

De Ley, Sophia

Depypere, Herman

Van Lierde, Kristiane

English

Ghent University Academic Bibliography

Purpose The purpose of this study was to investigate the speaking fundamental frequency (SFF) in pre- and postmenopausal women with and without hormone therapy (HT) and with low and high BMI.  D’haeseleer, E., Depypere, H., Van Lierde, K.M. (2013). Comparison of Speaking Fundamental Frequency between premenopausal woman and postmenopausal women with and without hormone therapy. Folia Phoniatrica et Logopaedica, 65, 78-83.    Comparison of Speaking Fundamental Frequency between premenopausal woman and postmenopausal women with and without hormone therapy. Evelien D’haeseleer, Sophia De Ley, Herman Depypere, Kristiane Van Lierde Department of Speech, Language and Hearing Sciences, Ghent University Department of Gynaecology, Ghent University Hospital Voice Assessment The mean SFF of connected speech was measured using Real-Time Pitch (Model 5121 V3.1.6) program from Computerized Speech Lab from Kay.  Background The voices of middle-aged women are subject to a combination of aging and menopausal transition. The menopause ends the reproductive period and is characterized by a decrease of the female sex hormones estrogen and progesterone. The hormone balance and the ratio of estrogen and progesterone to androgens changes and the influence of androgens becomes more important in the female body. In the postmenopause, ovarian contribution of estrogen is negligible, and adipose tissue becomes the main source of estrogen production . Hormone therapy (HT) has a long-standing tradition for the treatment of menopausal complaints. It compensates for the drop in endogenous estrogen and or progesterone levels in the postmenopause. It is known that sex hormones influences the female voice. When studying voice in middle-aged women a distinction should be made between premenopausal women, postmenopausal with HT and postmenopausal women without HT, with low and high BMI. Discussion The SFF of premenopausal women with low BMI was compared with the SFF of premenopausal women with high BMI, postmenopausal women with HT and low BMI, postmenopausal women with HT and high BMI, postmenopausal women without HT and with low BMI and postmenopausal women without HT and with high BMI. The results of this study show that the SFF of premenopausal women with low BMI (mean: 188.3Hz) only differed from the SFF of postmenopausal women without HT and with low BMI. (mean: 174.5Hz). The mean difference in SFF between these two groups was 14 Hz. This difference of 14Hz corresponds with 1.32 semitones or with 7.6% [188.8Hz-174.5Hz)/188.8Hz]. The results of this study suggest that the menopause lowers the voice with approximately 14Hz and that HT and adipose tissue (high BMI) might counteracts the menopausal drop in SFF.      LSD     p-value premenopausal women low BMI premenopausal women high BMI 0.837 postmenopausal women with HT low BMI 0.934 postmenopausal women with HT high BMI 0.937 postmenopausal women without HT low BMI 0.010   postmenopausal women without HT high BMI 0.428 n SFF ANCOVA     mean SD p-value premenopausal women low BMI 22 188.3 17.6 premenopausal women high BMI 13 189.6 15.1 postmenopausal women with HT low BMI 35 188.7 18.2 postmenopausal women with HT high BMI 19 187.8 22.6 postmenopausal women without HT low BMI 28 174.5 17.8 postmenopausal women without HT high BMI 12 183.0 11.3 0.016 165170175180185190premenopausalwomen low BMIpremenopausalwomen highBMIpostmenopausalwomen with HTlow BMIpostmenopausalwomen with HThigh BMIpostmenopausalwomen withoutHT low BMIpostmenopausalwomen withoutHT high BMISFF mean  Subjects               n Age (years) BMI time of menopause (years)     mean SD mean SD mean SD premenopausal women low BMI (<25) 22 48.5 2.3 21.6 1.9 premenopausal women high BMI (> 25) 13 48.1 2.3 29.0 4.4 postmenopausal women with HT low BMI (<25) 35 57.5 5.0 22.4 1.9 7.6 4.5 postmenopausal women with HT high BMI (> 25) 19 56.7 4.1 27.3 1.8 7.1 3.5 postmenopausal women without HT low BMI (< 25) 28 58.5 5.5 22.5 1.7 8.2 6.6 postmenopausal women without HT high BMI (> 25) 12 59.4 5.4 28.0 2.2 11.2 5.4 

Comparison of speaking fundamental frequency between premenopausal and postmenopausal women with and without hormone therapy

https://biblio.ugent.be/publication/4419435/file/4419452.pdf

Comparison of speaking fundamental frequency between premenopausal and postmenopausal women with and without hormone therapy

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Ghent University Academic Bibliography