Circos plots showing how marginally significant TWAS gene lists (P < 0.05) for each of the eight eQTL panels overlap.

Abstract

On the outside, the arc represents the eight eQTL panels. On the inside, the dark orange arc represents genes shared by several panels and the light orange arc represents genes unique to those panels. The purple lines link the genes shared by several panels. (A) The plot shows the shared genes between positively associated TWAS genes (TWAS Z-score > 0). (B) The plot shows shared genes between negatively associated TWAS genes (TWAS Z-score (TIF)</p