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Abstract

Section A. Comparison with other methods for discovering single driver mutation. Section B. Parameters analysis of CEBP. Section C. Selection of core genes in CEBP. Table A in S1 Text. The causal effect of TP53 mutation on DNA replication and EMT of BRCA under different numbers of hidden confounders settings. Table B in S1 Text. The causal effect of TP53 mutation on DNA replication and EMT of LUAD under different numbers of hidden confounders settings. Fig A in S1 Text. Fraction of predicted driver genes presents in CGC which consists 616 cancer-related mutations. Fig B in S1 Text. Heat maps of correlations between genes of DNA replication and EMT in BRCA, LUAD, and LIHC tumor samples, where the color indicates the correlation value and the number on the horizontal and vertical axes is the gene’s index. (DOCX)</p