The discontinuation or a break in the continuity of the covering epithelium of skin or mucous membrane is called as ulcer. The healing of the ulcer is a physiological response of the body. When a person does not maintain the proper treatment regimen, hygiene, along with indulgence of Ahita Ahara, Ahita Vihara and contaminated with various micro-organisms and developed a Dusta Vrana or non healing ulcer. Sushruta has described six types of Dusta Vrana. Bed sore can be co-related with Dusta Vrana. A single case of Dusta Vrana (bed sore) was successfully treated with local application of Yastimadhu Siddha Taila in Govt. Ayurvedic College and Hospital, Guwahati. Thus it has been observed that Yastimadhu Siddha Taila is a very effective drug in the management of Dusta Vrana