……………………………………………………………………………………………………… Abstract: The growth of Christianity in Ghana has led to the proliferation of liturgical changes leading to conflict of religious ideologies within the traditional (orthodox) and the modern (charismatic) churches. These liturgical modifications are seen not only in their worship, prayers and offerings but also in their music. This paper explores the changes that have taken place in the musical liturgy of the Methodist Church, Ghana. Through qualitative data collection, the paper investigates the factors leading to these changes and brings out the impact made in the Methodist church in general. It uses two epistemological frameworks: The separatism and the syncretism. The former looks at the liturgy in retrospect whereas the latter dwells on the changes culminating different beliefs as a result of the different movements in the Christendom in Ghana. To satisfy the varied congregational taste in this modern world, it is important that the shift in the musical liturgy of the Methodist church is well embraced by all