ボディエリアネットワークにおける動的通信チャネルモデルの構築

修士論

UVA Assisted 4-Thiothymidine for Cancer Treatment

This article reviews the developments of 4-thiothymidine analogues, assisted with UVA light, as a novel cancer therapy. First, the key points on synthetic chemistry, photochemistry and cellular toxicity of 4-thiothymidine are summarized. As the chemical structure of 4-thiothymidine is very similar to that of its parent thymidine, thus 4-thiothymidine can be readily incorporated into cellular DNA, and with the help of thymidine kinase, much more preferably into cancerous DNA. Unlike thymidine, 4-thiothymdine can absorb strongly in UVA (longer wavelengths of UV) light. Thus UVA-assisted 4-thiothymidine offers an effective cancer treatment. Some underlying mechanisms of action by 4-thiothymidine/UVA and compares this cancer approach with the commonly used photodynamic therapy are discussed. The various interactions between 4-thiothymidine with human serum albumin are introduced. Finally, a short conclusion on the past efforts and a brief prospect for future work in this exciting research field are given

The Reliability and Validity of FMS ver.a.j

福盛・森川（2003）によってフォーカシング的態度を測定する体験過程尊重尺度（the Focusing Manner Scale；FMS）が開発されて以来、FMS を用いた研究が日本国内では盛んになされてきた。それらの研究結果は、Aoki, Kawasaki & Miyake（2009）によって英語で概観が発表されるまでは日本語でのみ発表されており、海外の研究者に知られることはなかった。筆者は日本国内外の研究者らと共に、英語版を試作したが、その過程で改定が成され、原版のFMS とは異なる点がいくつかできた。筆者は、この改訂版FMSを体験過程尊重尺度青木版（the Focusing Manner Scale version a.; FMS ver.a.）と名付け、英語版をFMS ver.a.e とし、日本語版をFMS ver.a.j とした。本研究では、ひとまず日本語版の信頼性と妥当性を検討した。因子分析の結果、原版と同様の因子構造が認められ、因子的妥当性が示された。信頼性については、α係数が尺度全体で.75、各因子で.66、.55、 .64 であった。原版同様にGHQ28との相関分析を行った結果、両尺度の総得点では有意な弱い負の相関（r=-.26 p<.001, N=287）、FMS ver.a.j の各因子とGHQの下位項目群との間ではr=-.17（p<.01）からr=-.40（p<.001）と、原版とおおよそ同程度の負の相関が認められた。GHQ28は心理学的、医学的な症状を測定するものであるため、これらの結果から、FMS ver.a.j の併存的妥当性が示された。Since the Focusing Manner Scale (FMS) which measures Focusing Attitudes has been developed by Fukumori & Morikawa (2003), FMS had been utilized in many researches. The outcomes of those FMS researches had been reported only in Japanese until Aoki, Kawasaki &　Miyake (2009) reviewed them in English. In collaboration with English speaking researchers, the author attempted to make an English version of FMS which entailed some revisions in the original FMS. This revised FMS is named the Focusing Manner Scale version a. (FMS ver.a.), "version a." signifies the version rivised by Aoki, and its Japanese and English versions are named　FMS ver.a.j, and FMS ver.a.e, respectively. In this paper, the author demonstrated the validity and　reliability of FMS ver.a.j. Factor analysis showed that FMS ver.a.j had an almost identical 3-factor structure as the original FMS and confirmed the factorial validity of FMS ver.a.j. The Cronbach alpha coefficient of the whole scale was .75 and each of the 3 factors was .66, .55, and .64. These Cronbach alpha coefficients confirmed the reliability of FMS ver.a.j. Finally, correlation analysis with GHQ28 a measure of psychological and somatic symptoms, revealed almost the same correlations as FMS did in the original study. FMS ver.a.j correlated negatively with GHQ28 total (r=-.26 p<.001, N=287), and the negative correlations of the subscales of FMS ver. a.j and GHQ items were between r=-.17(p<.01) and r=-.40(p<.001). Since GHQ28 measures psychological and somatic symptoms, these results confirm the concurrent validity of FMS ver.a.j

社会的勢力が自己欺瞞，印象操作および原因帰属に及ぼす影響の検討

In this study, We investigated that effect of perceived social power on self-deception, impression management, and causal attribution. Participants were university students and they answered three questionnaires on their university class. As a result, perceived social power was positively correlate to self-deception（ r=.47, p<.001） but impression management was not correlate social power and self-deception. High power participants was more attributed to their ability, but no such effect was detected in low power participants

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黒田研二教授退職記念