74,178 research outputs found

    Dirac Coupled-channel Analyses of Polarized Proton Scatterings to the 2+^+ Gamma Vibrational Band in 24^{24}Mg and 26^{26}Mg

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    Dirac coupled channel calculations are performed phenomenologically for the high-lying excited states that belong to the 2+^+ gamma vibrational band at the 800-MeV polarized proton inelastic scatterings from the s-d shell nuclei, 24^{24}Mg and 26^{26}Mg. Optical potential model is used and scalar and time-like vector potentials are considered as direct potentials. First-order vibrational collective models are used to obtain the transition optical potentials in order to accommodate the high-lying excited vibrational collective states. The complicated Dirac coupled channel equations are solved phenomenologically to reproduce the differential cross section and analyzing power data by varying the optical potential and deformation parameters. It is found that the relativistic Dirac coupled channel calculation could describe the high-lying excited states of the 2+^+ gamma vibrational band at the 800-MeV polarized proton inelastic scatterings from s-d shell nuclei 24^{24}Mg and 26^{26}Mg reasonably well, showing better agreement with the experimental data compared to the results obtained from the nonrelativistic calculations. Calculated deformation parameters for the excited states are analyzed and compared with those of nonrelativistic calculations.Comment: 13pages, 6 figures. arXiv admin note: text overlap with arXiv:1501.00650, arXiv:1407.5441, arXiv:1511.0172

    Analysis of antenal sensilla patterns of Rhodnius prolixus from Colombia and Venezuela

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    Antennal sensilla patterns were used to analyze population variation of domestic Rhodnius prolixus from six departments and states representing three biogeographical regions of Colombia and Venezuela. Discriminant analysis of the patterns of mechanoreceptors and of three types of chemoreceptors on the pedicel and flagellar segments showed clear differentiation between R. prolixus populations east and west of the Andean Cordillera. The distribution of thick and thin-walled trichoids on the second flagellar segment also showed correlation with latitude, but this was not seen in the patterns of other sensilla. The results of the sensilla patterns appear to be reflecting biogeographic features or population isolation rather than characters associated with different habitats and lend support to the idea that domestic R. prolixus originated in the eastern region of the Andes.Fil: Esteban, Lyda. Universidad Industrial de Santander; ColombiaFil: Angulo, VĂ­ctor Manuel. Universidad Industrial de Santander; ColombiaFil: Dora Feliciangeli, M.. Universidad de Carabobo; VenezuelaFil: Catala, Silvia Susana. Consejo Nacional de Investigaciones CientĂ­ficas y TĂ©cnicas. Centro Regional de Investigaciones CientĂ­ficas y Transferencia TecnolĂłgica de La Rioja. - Universidad Nacional de La Rioja. Centro Regional de Investigaciones CientĂ­ficas y Transferencia TecnolĂłgica de La Rioja. - Universidad Nacional de Catamarca. Centro Regional de Investigaciones CientĂ­ficas y Transferencia TecnolĂłgica de La Rioja. - SecretarĂ­a de Industria y MinerĂ­a. Servicio GeolĂłgico Minero Argentino. Centro Regional de Investigaciones CientĂ­ficas y Transferencia TecnolĂłgica de La Rioja. - Provincia de La Rioja. Centro Regional de Investigaciones CientĂ­ficas y Transferencia TecnolĂłgica de La Rioja; Argentin

    Mechanisms in Adaptive Feedback Control: Photoisomerization in a Liquid

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    The underlying mechanism for Adaptive Feedback Control in the experimental photoisomerization of NK88 in methanol is exposed theoretically. With given laboratory limitations on laser output, the complicated electric fields are shown to achieve their targets in qualitatively simple ways. Further, control over the cis population without laser limitations reveals an incoherent pump-dump scenario as the optimal isomerization strategy. In neither case are there substantial contributions from quantum multiple-path interference or from nuclear wavepacket coherence. Environmentally induced decoherence is shown to justify the use of a simplified theoretical model.Comment: 10 pages, 3 figures, to be published in Phys. Rev. Let

    Photometric Calibration of the Supernova Legacy Survey Fields

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    We present the photometric calibration of the Supernova Legacy Survey (SNLS) fields. The SNLS aims at measuring the distances to SNe Ia at (0.3<z<1) using MegaCam, the 1 deg^2 imager on the Canada-France-Hawaii Telescope (CFHT). The uncertainty affecting the photometric calibration of the survey dominates the systematic uncertainty of the key measurement of the survey, namely the dark energy equation of state. The photometric calibration of the SNLS requires obtaining a uniform response across the imager, calibrating the science field stars in each survey band (SDSS-like ugriz bands) with respect to standards with known flux in the same bands, and binding the calibration to the UBVRI Landolt standards used to calibrate the nearby SNe from the literature necessary to produce cosmological constraints. The spatial non-uniformities of the imager photometric response are mapped using dithered observations of dense stellar fields. Photometric zero-points against Landolt standards are obtained. The linearity of the instrument is studied. We show that the imager filters and photometric response are not uniform and publish correction maps. We present models of the effective passbands of the instrument as a function of the position on the focal plane. We define a natural magnitude system for MegaCam. We show that the systematics affecting the magnitude-to-flux relations can be reduced if we use the spectrophotometric standard star BD +17 4708 instead of Vega as a fundamental flux standard. We publish ugriz catalogs of tertiary standards for all the SNLS fields.Comment: 46 pages, 23 figures. Accepted by Astronomy and Astrophysics. Online material available at the CDS via anonymous ftp to cdsarc.u-strasbg.fr (130.79.128.5) or http://cdsweb.u-strasbg.fr/cgi-bin/qcat?J/A+A/ or alternatively from: http://supernovae.in2p3.fr/snls3/regnault09_cds.tar.g

    Study of meta-analysis strategies for network inference using information-theoretic approaches

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    © 2017 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.Reverse engineering of gene regulatory networks (GRNs) from gene expression data is a classical challenge in systems biology. Thanks to high-throughput technologies, a massive amount of gene-expression data has been accumulated in the public repositories. Modelling GRNs from multiple experiments (also called integrative analysis) has; therefore, naturally become a standard procedure in modern computational biology. Indeed, such analysis is usually more robust than the traditional approaches focused on individual datasets, which typically suffer from some experimental bias and a small number of samples. To date, there are mainly two strategies for the problem of interest: the first one (”data merging”) merges all datasets together and then infers a GRN whereas the other (”networks ensemble”) infers GRNs from every dataset separately and then aggregates them using some ensemble rules (such as ranksum or weightsum). Unfortunately, a thorough comparison of these two approaches is lacking. In this paper, we evaluate the performances of various metaanalysis approaches mentioned above with a systematic set of experiments based on in silico benchmarks. Furthermore, we present a new meta-analysis approach for inferring GRNs from multiple studies. Our proposed approach, adapted to methods based on pairwise measures such as correlation or mutual information, consists of two steps: aggregating matrices of the pairwise measures from every dataset followed by extracting the network from the meta-matrix.Peer ReviewedPostprint (author's final draft

    Technical and economic feasibility of gradual concentric chambers reactor for sewage treatment in developing countries

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    A major challenge in developing countries concerning domestic wastewaters is to decrease their treatment costs. In the present study, a new cost-effective reactor called gradual concentric chambers (GCC) was designed and evaluated at lab-scale. The effluent quality of the GCC reactor was compared with that of an upflow anaerobic sludge bed (UASB) reactor. Both reactors showed organic matter removal efficiencies of 90%; however, the elimination of nitrogen was higher in the GCC reactor. The amount of biogas recovered in the GCC and the UASB systems was 50% and 75% of the theoretical amount expected, respectively, and both reactors showed a slightly higher methane production when the feed was supplemented with an additive based on vitamins and minerals. Overall, the economical analysis, the simplicity of design and the performance results revealed that the GCC technology can be of particular interest for sewage treatment in developing countries

    Seasonal variation of arsenic concentrations in tubewells in west Bengal, India.

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    This study was conducted to monitor the changes in arsenic concentration during different seasons in a one-year period during 2002-2003 in selected tubewells in an arsenic-affected area in the district of South 24 Parganas in West Bengal, India, and to map the location of the wells. Seasonal variations in concentrations of arsenic in water were measured from 74 selected tubewells, ranging in depth from 40 to 500 feet. Water samples were collected from these wells during winter, summer, monsoon, and the following winter in 2002-2003. A global positioning system was used for locating the tubewells, and a geographic information system was used for mapping. There was evidence of seasonal variation in concentrations of arsenic in water (p=0.02) with the minimum average concentration occurring in the summer season (694 microg/L) and the maximum in the monsoon season (906 microg/L). From the winter of 2002 to the winter of 2003, arsenic concentrations increased, irrespective of the depth of the tubewells, from an average of 464 microg/L to 820 microg/L (p&lt;0.001). This extent of variation in arsenic concentration, if confirmed, has important implications for both epidemiological research and mitigation programmes

    In vitro inhibition of Helicobacter pylori urease with non and semi fermented Camellia sinensis

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    Purpose: Helicobacter pylori is the etiological agent in duodenal and peptic ulcers. The growing problem of antibiotic resistance by the organism demands the search for novel compounds, especially from natural sources. This study was conducted to evaluate the effect of Camellia sinensis extracts on the urease enzyme that is a major colonization factor for H. pylori. Methods: Minimum inhibitory concentrations of nonfermented and semifermented C. sinensis methanol: water extracts were assessed by broth dilution method. Examination of the urease function was performed by Mc Laren method, and urease production was detected on 12% SDS polyacrylamide gel electrophoresis from whole cell and membrane bound proteins. Results: Both extracts had inhibitory effects against H. pylori and urease production. At a concentration of 2.5 mg/ml of nonfermented extract and 3.5 mg/ml of semifermented extract the production of Ure A and Ure B subunits of the urease enzyme were inhibited completely. A concentration of 4 mg/ml of nonfermented and 5.5 mg/ml of semifermented extract were bactericidal for H. pylori. Conclusions: C. sinensis extracts, especially the nonfermented, could reduce H. pylori population and inhibit urease production at lower concentrations. The superior effect of nonfermented extract is due to its rich polyphenolic compounds and catechin contents

    Looking inside the black box : a theory-based process evaluation alongside a randomised controlled trial of printed educational materials (the Ontario printed educational message, OPEM) to improve referral and prescribing practices in primary care in Ontario, Canada

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    Background: Randomised controlled trials of implementation strategies tell us whether (or not) an intervention results in changes in professional behaviour but little about the causal mechanisms that produce any change. Theory-based process evaluations collect data on theoretical constructs alongside randomised trials to explore possible causal mechanisms and effect modifiers. This is similar to measuring intermediate endpoints in clinical trials to further understand the biological basis of any observed effects (for example, measuring lipid profiles alongside trials of lipid lowering drugs where the primary endpoint could be reduction in vascular related deaths). This study protocol describes a theory-based process evaluation alongside the Ontario Printed Educational Message (OPEM) trial. We hypothesize that the OPEM interventions are most likely to operate through changes in physicians' behavioural intentions due to improved attitudes or subjective norms with little or no change in perceived behavioural control. We will test this hypothesis using a well-validated social cognition model, the theory of planned behaviour (TPB) that incorporates these constructs. Methods/design: We will develop theory-based surveys using standard methods based upon the TPB for the second and third replications, and survey a subsample of Ontario family physicians from each arm of the trial two months before and six months after the dissemination of the index edition of informed, the evidence based newsletter used for the interventions. In the third replication, our study will converge with the "TRY-ME" protocol (a second study conducted alongside the OPEM trial), in which the content of educational messages was constructed using both standard methods and methods informed by psychological theory. We will modify Dillman's total design method to maximise response rates. Preliminary analyses will initially assess the internal reliability of the measures and use regression to explore the relationships between predictor and dependent variable (intention to advise diabetic patients to have annual retinopathy screening and to prescribe thiazide diuretics for first line treatment of uncomplicated hypertension). We will then compare groups using methods appropriate for comparing independent samples to determine whether there have been changes in the predicted constructs (attitudes, subjective norms, or intentions) across the study groups as hypothesised, and will assess the convergence between the process evaluation results and the main trial results.The OPEM trial and OPEM process evaluation are funded by the Canadian Institute of Health Research (CIHR). The OPEM process evaluation study was developed as part of the CIHR funded interdisciplinary capacity enhancement team KT-ICEBeRG. Gaston Godin, Jeremy Grimshaw and France Légaré hold Canada Research Chairs. Louise Lemyre holds an R.S. McLaughlin Research Chair
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