Plant disease control: understanding the roles of toxins and phytoalexins in host-pathogen interaction

Naturally, plant habitats are exposed to several potential effects of biotic and different abiotic environmental challenges. Several types of micro-organisms namely; bacteria, viruses, fungi, nematodes, mites, insects, mammals and other herbivorous animals are found in large amounts in all ecosystems, which lead to considerable reduction in crop productivity. These organisms are agents carrying different diseases that can damage the plants through the secretion of toxic-microbial poisons that can penetrate in the plant tissues. Toxins are injurious substances that act on plant protoplast to influence disease development. In response to the stress effect, plants defend themselves by bearing some substances such as phytoalexins. Production of phytoalexins is one of the complex mechanisms through which plants exhibit disease resistance. Several findings specifically on phytoalexins have widen the understanding in the fields of plant biochemistry and molecular biology. However, this review reports the interaction of toxins and phytoalexins in plant-pathogen cycle, research progress on the association of phytoalexins with plant disease resistance as well as the role of the phytoalexins in plant disease control

Overview of brown bast syndrome of Hevea brasiliensis

Hevea brasiliensis is one of the popular industrial crops in Malaysia better known as rubber tree belongs to the family Euphorbiaceace. From more than 12 species of Hevea, only Hevea brasiliensis is economically exploited because the milky latex extracted from the tree is the primary source of natural rubber. As in other crops, various plant physiological conditions and pathogenic diseases influence rubber production. Brown bast is one of the most serious threats to natural rubber production. In general, high-yielding clones of rubber tree are often considered to be more susceptible to this physiological disorder also commonly termed Tapping Panel Dryness (TPD). It is estimated that brown bast leads to approximately 15-20% decrease in yield. There is no known cure for brown bast yet. However, many plantation practices manage brown bast in rubber by giving tapping rest and changing tapping panel. Hence, this review condenses the causal of brown bast, symptoms of diseases and also control of brown bast affected Hevea tree

Deficient Reinforced Concrete Beam-Column Joint Strengthening

Structural buildings in seismic prone area, the required energy dissipation of strong column-weak beam especially for reinforced concrete frame structures is achievably through adequate beam-column joint strengthening connection in order to have high seismic performance. Literature investigation shows several approaches and techniques for modelling the weak joint for a typical frame structure. This paper extensively reviews those techniques, methods, concepts and their performance in improving the shear capacity for a deficient reinforced concrete beam-column joints in withstanding seismic loads. The beam-column joints performance responses showed positive. However, the need for an improved connection that will offer high ductility capacity and energy dissipation ability for post-tensioned reinforced concrete beam-column joints with continuing bottom reinforcement is highly feasible with the use of the Direct Displacement Based design philosophy. This will be of great interest for the future development of highly efficient joint system for frame structure capable of resisting significant seismic load

Prospective Therapeutic Strategies for Cervical Cancer

Abstract – Cervical cancer is one of the leading causal cancer-related fatalities in the world. Cervical cancer patients can be treated by conventional treatment such as surgery, radiotherapy, chemotherapy, medications and combination treatments. Currently, more targeted treatments are being developed to cure cervical cancer. The treatments include immunotherapy, virotherapy and gene therapy which will be discussed in this paper. In immunotherapy, the synergy of CTLA-4 suppression and PD-1/PDL-1 immune checkpoint inhibition targeting their corresponding pathways enhanced the human immune system resulting a promising treatment effects. Oncolytic viruses such as Newcastle disease virus selectively infect and kill cancerous cells/tissues without harming normal cells/tissues. This character has made them a potential modality in combating cancer which popularly known as oncolytic virotherapy. Gene therapy delivers modified genetic materials to the target cancer cells via viral and non-viral vectors. It is used to target the abnormal gene, to increase cells’ susceptibility towards drugs or conventional therapy, to induce tumour cells apoptosis, to enhance tumour cell immunogenicity recognition and to inhibit the oncogene expression. The objective of this minireview is to add to the general knowledge on aforementioned therapeutic strategies against cervical cancer

Critical Review on Factors That Influence Continuous Engagement Towards CCBT

Substance abuse is an epidemic that spreads among adults, adolescents and even children in Malaysia. Substance abuse is categorized as a mental disorder, whereby, Cognitive Behavioural Therapy (CBT) is an approach that provides face to face physiological therapy for patients could resolve this issue. Computerized Cognitive Behavioural Therapy (CCBT) is a progression of information technology that is provided for patients encounter substance abuse. CCBT is a computerized therapy conducted at patient’s own pace. Ensuring patient’s continuous engagement towards CCBT becomes an issue. Patients that experience early gains, loss of interest and improvement symptom would sign up for alternative services that eventually causes disengagement and dropout from CCBT program. Interface design for CCBT is known as one of the important elements that effects patient’s engagement along CCBT program. Therefore, in this study, influential factors regarding CCBT’s interface design was investigated, whereby, five prominent models was reviewed. Content analysis methodology was employed to discover influential factors regarding CCBT’s interface design. Four influential factors was discovered namely engagement, dropout, culture and interface. These factors are known to ensure patient’s continuous engagement towards CCBT program. CCBT’s interface design plays a vital role in delivering the therapy program. Indirectly, CCBT’s interface design plays an important role to ensure patient’s continuous engagement till the completion of CCBT program. Therefore, these factors would guide researcher, service provider, developers and clinicians in designing engaging interface for CCBT

Plant Disease Control: Understanding the Roles of Toxins and Phytoalexins in Host-Pathogen Interaction

Naturally, plant habitats are exposed to several potential effects of biotic and different abiotic environmental challenges. Several types of micro-organisms namely; bacteria, viruses, fungi, nematodes, mites, insects, mammals and other herbivorous animals are found in large amounts in all ecosystems, which lead to considerable reduction in crop productivity. These organisms are agents carrying different diseases that can damage the plants through the secretion of toxic-microbial poisons that can penetrate in the plant tissues. Toxins are injurious substances that act on plant protoplast to influence disease development. In response to the stress effect, plants defend themselves by bearing some substances such as phytoalexins. Production of phytoalexins is one of the complex mechanisms through which plants exhibit disease resistance. Several findings specifically on phytoalexins have widen the understanding in the fields of plant biochemistry and molecular biology. However, this review reports the interaction of toxins and phytoalexins in plant-pathogen cycle, research progress on the association of phytoalexins with plant disease resistance as well as the role of the phytoalexins in plant disease control

Ozone Application in Fresh Fruits and Vegetables

The demand of fruits and vegetables across the world had increased throughout the years which urge the need to have better and proper way to increase produce safety, quality and postharvest life. Traditionally pesticides or other chemicals had been used to encounter microbes related to postharvest diseases. Over time, consumers are concern towards health effect of consuming those produce treated with chemicals. Ozone is one of the approach that provide both of the needs to deal with pathogenic microbes and also give no harmful residue throughout the process. Several reports had proven that ozone can almost kill or inhibit all pathogenic microbes on treated commodity which promote higher quality and postharvest life during storage. This review focus and summarise the use of ozone in the form of aqueous and gaseous towards fresh produces, its benefits and also the precaution during ozone application

A Case Study on Culture-Oriented Design Preferences

It is hard to identify the local Malay identity in a design context compared to other cultural oriented design in several countries. This paper tries to uncover how designers interpret local identity embodied agent based on local items influences and understood and the influence of incremental, radical design that changes respective to preceding designs. A descriptive study through the literature reviews focusses on a type of artefact initiated through cultural-oriented design. Based on the preliminary study, a sampling taken from the Chinese, Indian, Japanese or European consistently apply the same fundamental understanding in regards to the culture-oriented design. From the same point of view, teapot seems to be used as one of the dominant artefact indicating the design preferences. This research will benefit both the academia and the industry and identify significant identity based on the local context and become an embodied agent to give impact in establishing  the state-of-the-art of brand, the identity of local design, establish new trademark towards generating domestic, international economy and promote the nation worldwide throughout design platform

Crowdfunding as Financial Option for Small and Medium Enterprises (SMEs) in Nigeria

Abstract Small and medium scale enterprises (SMEs) act as a promoter of economic development of the developed and under developed nations. Developing countries like Nigeria that, require sustainable economic growth and development must pay attention to the SMEs sectors in order to reduce unemployment, poverty and improve the standard leaving of its society. Unfortunately, in Nigeria, SMEs have underperformed despite that, 90% of the Nigerian businesses are small scales but their contribution to the Nigerian GDP is below 10%. The main reason for this low contribution of SMEs to Nigerian GDP could be attributed to poor funding, lack of management expertise and lack of access to modern technology among others, with proper finance the SMEs can acquire modern technology and employed qualified staff.  Thus, this paper focuses on crowdfunding as financial option for small and medium enterprises in Nigeria. However the paper is based on conceptual framework.

Effect ofZingiber officinaleon Spasm

Zingiberaceae is one of the largest plant families consisting of rhizomes that are commonly used as spice in soups and curries as well as alternative medications in folklore medicine. Zingiber officinale or commonly known as ginger is extensively employed in Asian, Ayurvedic, Chinese, and Arabian folklore medicine for the treatment of pain, inflammation and various spasm-associated gastric ailments. The past few decades saw rapid advancements in the extraction process of ginger bioactive constituents and validation of their corresponding pharmacodynamic and pharmacotherapeutic activities, and biological properties in vivo and in vitro. Results reported from several biological studies on ginger showed that extracts and compounds from this tuberous rhizome exhibit antiemetic, anticancer, antipyretic, antispasmogenic and antimicrobial activities. This article reviews the effect of Zingiber officinale and its bioactive constituents on isolated organ preparations from several species of animals in view of its potential use as an alternative treatment for muscle spasms and common gastric ailments